Paul Jedlicka Selected Research

Homeodomain Proteins (Proteins, Homeobox)

12/2014	Homeoprotein Six2 promotes breast cancer metastasis via transcriptional and epigenetic control of E-cadherin expression.
9/2009	Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition.
9/2009	The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling.
4/2008	Six1 overexpression in mammary cells induces genomic instability and is sufficient for malignant transformation.

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Paul Jedlicka Research Topics

Disease

29	Neoplasms (Cancer) 01/2020 - 08/2006
13	Ileitis 01/2020 - 05/2010
12	Inflammation (Inflammations) 10/2018 - 10/2011
12	Breast Neoplasms (Breast Cancer) 10/2016 - 09/2006
10	Colitis 01/2022 - 10/2011
10	Neoplasm Metastasis (Metastasis) 01/2020 - 09/2006
9	Ewing Sarcoma (Sarcoma, Ewing) 10/2020 - 03/2010
7	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2022 - 05/2010
6	Crohn Disease (Crohn's Disease) 01/2019 - 05/2011
4	Carcinoma (Carcinomatosis) 10/2014 - 06/2009
4	Carcinogenesis 01/2013 - 01/2004
3	Triple Negative Breast Neoplasms 10/2016 - 10/2014
2	Eosinophilia 10/2015 - 05/2010
2	Necrosis 08/2015 - 08/2012
2	Tics (Tic) 10/2014 - 07/2012
2	Hypoxia (Hypoxemia) 12/2013 - 10/2012
2	Lymphatic Metastasis 05/2012 - 11/2007
1	Rhabdomyosarcoma 01/2022
1	Sarcoma (Soft Tissue Sarcoma) 01/2022
1	Lymphopenia (Lymphocytopenia) 01/2020
1	Fibrosis (Cirrhosis) 10/2015
1	Pathologic Constriction (Stenosis) 10/2015
1	Neoplasm Micrometastasis 12/2014
1	Lipoma (Lipomata) 12/2014

Drug/Important Bio-Agent (IBA)

10	Transcription Factors (Transcription Factor)IBA 01/2022 - 01/2004
7	CytokinesIBA 01/2022 - 05/2010
6	MicroRNAs (MicroRNA)IBA 01/2019 - 08/2012
5	Dextran SulfateIBA 01/2020 - 03/2011
4	Phenobarbital (Luminal)FDA Link 01/2022 - 07/2012
4	Estrogen ReceptorsIBA 10/2016 - 09/2006
4	Proteins (Proteins, Gene)FDA Link 10/2016 - 08/2012
4	Homeodomain Proteins (Proteins, Homeobox)IBA 12/2014 - 04/2008
4	Estradiol (Delestrogen)FDA LinkGeneric 12/2014 - 09/2006
4	Estrogens (Estrogen)FDA Link 12/2014 - 09/2006
3	Histone DemethylasesIBA 01/2020 - 09/2018
3	Oncogene Proteins (Oncogene Protein)IBA 09/2018 - 01/2013
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2014 - 05/2011
3	Oxygen (Dioxygen)IBA 01/2014 - 10/2012
2	JIB-04IBA 01/2020 - 09/2018
2	Messenger RNA (mRNA)IBA 01/2020 - 04/2008
2	Dextrans (Dextran)FDA Link 09/2017 - 01/2016
2	Interleukin-6 (Interleukin 6)IBA 01/2016 - 08/2015
2	AcidsIBA 08/2015 - 12/2014
2	Chemokine ReceptorsIBA 06/2015 - 05/2011
2	Androgen Receptors (Androgen Receptor)IBA 03/2015 - 01/2014
2	enzalutamideIBA 03/2015 - 01/2014
2	Hormones (Hormone)IBA 12/2014 - 09/2006
2	EnzymesIBA 12/2014 - 12/2013
2	Vascular Endothelial Growth Factor CIBA 10/2014 - 05/2012
2	Biomarkers (Surrogate Marker)IBA 01/2013 - 01/2013
2	Proto-Oncogene Proteins c-etsIBA 08/2012 - 06/2009
2	Transforming Growth Factor beta (TGF-beta)IBA 07/2012 - 09/2009
2	Progesterone Receptors (Progesterone Receptor)IBA 11/2007 - 09/2006
1	Immunoglobulin A (IgA)IBA 01/2022
1	Immunoglobulins (Immunoglobulin)IBA 01/2022
1	IntegrinsIBA 01/2022
1	Retinal DehydrogenaseIBA 01/2022
1	Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule)IBA 10/2020
1	LyasesIBA 01/2020
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2020
1	16S Ribosomal RNAIBA 01/2020
1	imidazoleIBA 01/2020
1	sphingosine 1-phosphate lyase (aldolase)IBA 01/2020
1	4-deoxypyridoxineIBA 01/2020
1	Interleukin-10 (Interleukin 10)IBA 01/2019
1	Adenosine (Adenocard)FDA LinkGeneric 10/2018
1	Analgesics (Analgesic Drugs)IBA 10/2017
1	CannabinoidsIBA 10/2017
1	LigandsIBA 10/2017
1	EndocannabinoidsIBA 10/2017
1	Cannabinoid Receptors (Cannabinoid Receptor)IBA 10/2017
1	AntigensIBA 09/2017
1	SodiumIBA 09/2017
1	LactoferrinIBA 09/2017
1	InflammasomesIBA 01/2017
1	AntibodiesIBA 10/2016
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2016
1	Interleukin-5 (Interleukin 5)IBA 01/2016
1	Interleukin-33IBA 10/2015
1	OxazoloneIBA 08/2015
1	Nitric Oxide Synthase (NO Synthase)IBA 08/2015
1	LipidsIBA 08/2015
1	Vincristine (Oncovin)FDA LinkGeneric 01/2015
1	3- (8- amino- 1- (2- phenylquinolin- 7- yl)imidazo(1,5- a)pyrazin- 3- yl)- 1- methylcyclobutanolIBA 01/2015
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2015
1	Cadherins (E-Cadherin)IBA 12/2014
1	AgarIBA 12/2014
1	Progestins (Progestagens)IBA 12/2014
1	Progesterone FDA LinkGeneric 12/2014
1	Fatty Acids (Saturated Fatty Acids)IBA 12/2014
1	Tumor Viral Antigens (Large T Antigen)IBA 12/2014
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 12/2014
1	Thyroid HormonesIBA 12/2014
1	Phospholipids (Phosphatides)FDA LinkGeneric 12/2014
1	ClaudinsIBA 10/2014
1	Superoxide DismutaseIBA 10/2014

Therapy/Procedure

11	Therapeutics 01/2022 - 05/2010
4	Drug Therapy (Chemotherapy) 12/2014 - 08/2012
1	Oral Administration 01/2020
1	Contraception (Birth Control) 12/2014